He was graduated from the University of Turin and in the post doc period obtained degrees in Radiotherapy, Medical Oncology and Diagnostic Imaging. Since 1994, he is Full Professor in Radiotherapy at the University of Milan and Director of the Radiology Science Department at IEO (European Institute of Oncology). Since January 2015 he is Scientific Director at the (IEO), in Milan, and at the CNAO Foundation, the first centre for hadrontherapy built in Italy, providing proton and carbon ion beams. His clinical and research activities focuse on different fields of radiation therapy and oncology, being since the beginning characterized by a strong interest for innovation. He published totally up to date more than three hundred fifty scientific papers on journals listed in the Pub-Med.